Intracerebral Hemorrhages Associated With Neurointerventional Procedures Using a Combination of Antithrombotic Agents Including Abciximab

Intracerebral hemorrhages associated with neurointerventional procedures using a combination of antithrombotic agents including abciximab.

BACKGROUND We report the occurrence of fatal intracerebral hemorrhage associated with using a combination of antithrombotic agents, including abciximab, in patients undergoing neurointerventional procedures. SUMMARY OF REPORT Seven patients (average age 60, range 46 to 73 years) developed fatal intracerebral hemorrhages associated with neurointerventional procedures and the use of intravenous...

HIV-associated multiple intracerebral hemorrhages.

Prevalence and clinical characteristics of intracerebral hemorrhages associated with clopidogrel.

BACKGROUND As clopidogrel is being increasingly used, intracerebral hemorrhage (ICH) associated with clopidogrel are expected to increase. We assessed the prevalence and clinical characteristics of of ICH with clopidogrel in a consecutive series of patients in two hospitals. METHODS We retrospectively reviewed the medication history of 204 patients (112 in one hospital and 92 in another - bot...

Antithrombotic effects of abciximab.

The observation that platelet-platelet interaction and thrombosis are ultimately regulated by the glycoprotein (GP) IIb/IIIa receptor complex, triggered the development of agents capable of interfering with this platelet receptor complex. Several large clinical trials have demonstrated the effectiveness of this class of agents. The first of these agents to show beneficial effects after coronary...

Use of antithrombotic agents in patients with intracerebral cavernous malformations.

OBJECT The goal of this study was to determine the risk of using antithrombotic agents in patients with established intracerebral cavernous malformations (ICMs). METHODS From a previously described cohort of 292 patients with radiographically defined ICMs, 40 required an antithrombotic after the ICM was diagnosed. Patients underwent follow-up to determine the incidence of hemorrhage. RESULT...